Name: Carbofuran Impurity 8 - SRIRAMCHEM
SKU: SAC-05-H
Price: 50000.00 INR
Availability: InStock

Sale!

Carbofuran Impurity 8,Name:3-Hydroxy Carbofuran, CAS NO.:16655-82-6

AgrochemicalsCarbofuran Impurity 8

SKU: SAC-05-H

Original price was: ₹60,000.00.Current price is: ₹50,000.00.

Name:3-Hydroxy Carbofuran CAT. NO.:SAC-05-H CAS NO.:16655-82-6

Description
Datasheet
Additional information

Description

Carbofuran Impurity 8

Chemical Name	3-Hydroxy Carbofuran
Catalog Number	SAC-05-H
Parent AI	Carbofuran
Synonyms	2,3-Dihydro-2,2-dimethyl-3,7-benzofurandiol 7-(N-Methylcarbamate); Methylcarbamic Acid 2,3-Dihydro-3-hydroxy-2,2-dimethyl-7-benzofuranyl Ester; 2,3-Dihydro-2,2-dimethyl-3-hydroxy-7-benzofuranyl N-Methylcarbamate
CAS Number	16655-82-6
Molecular Formula	C₁₂H₁₅NO₄
Molecular Weight	237.25
Appearance	White to Off-White Solid
Melting Point	>143°C (dec.)
Shipping & Storage Information	Storage-20°C Shipping: Free Shipping at Room Temperature in INDIA, may vary elsewhere Stability: Datasheet
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Stability	Stable under recommended storage conditions
Category	Agrochemical Impurity Standard/Metabolites;
Description &Applications	3-Hydroxycarbofuran (3-HCF) is a naturally occurring heterocyclic compound found in a variety of plants and fungi. It is a versatile and widely studied molecule, with applications in synthetic chemistry, medicinal chemistry, and biochemistry. 3-Hydroxy Carbofuran is a metabolite of Carbofuran (C176590) obtained from the rice field ecosystem in China (1). Usually found in residues obtained from fruits, grains and vegetables and may be extracted with the use of ethyl acetate (2) and through UPLC-MS/MS (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References	1. Zhang, C. et al.: J. Environ. Sci. Health. B. 2016;51(6):351-7. 2. PihlstrÃ¶m, T. et al.: Anal. Bioanal. Chem. 2007 Nov;389(6):1773-89. 3. Kovalczuk, T. et al.: Food Addit. Contam. Part. A. Chem. Anal. Control. Expo. Risk. Assess. 2008 Apr;25(4):444-57.

3-Hydroxy Carbofuran, a derivative of the well-known insecticide carbofuran, is a compound of significant interest due to its biological and chemical properties. Carbofuran, itself a cholinesterase inhibitor used to control various pests in agriculture, has been a subject of extensive study. The introduction of the hydroxy group to carbofuran’s structure adds a new dimension to its effects and potential applications. This article delves into the characteristics, uses, and potential implications of 3-Hydroxy Carbofuran.

Chemical Structure and Properties: The chemical structure of 3-Hydroxy Carbofuran consists of a furan ring, a carbamate functional group, and a hydroxy group attached to the third carbon of the furan ring. This structural modification alters the compound’s properties compared to its parent compound, carbofuran. The introduction of the hydroxy group can lead to changes in solubility, reactivity, and interactions with biological systems.

Biological Activity: Like carbofuran, 3-Hydroxy Carbofuran exhibits potent acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibitory activities. These enzymes play crucial roles in neurotransmission, and their inhibition can lead to the accumulation of acetylcholine at nerve synapses, resulting in overstimulation and eventual paralysis of insects. The hydroxy group in 3-Hydroxy Carbofuran likely contributes to its interaction with these enzymes, but research is ongoing to elucidate the precise mechanisms.

Applications:

Agriculture: While carbofuran has been widely used as an insecticide, 3-Hydroxy Carbofuran might offer improved efficacy, reduced environmental impact, or altered target specificity. Researchers are exploring its potential as an alternative to traditional insecticides or as a component of integrated pest management strategies.
Biomedical Research: The cholinesterase inhibitory properties of 3-Hydroxy Carbofuran could find applications in biomedical research related to neurology and toxicology. Studying its interactions with cholinesterase enzymes could provide insights into neurodegenerative diseases and the development of antidotes for nerve agent poisoning.
Environmental Monitoring: Due to its specific mode of action and potential impact on non-target organisms, 3-Hydroxy Carbofuran might have applications in monitoring and assessing the health of ecosystems. Its selective toxicity could make it a valuable tool in evaluating the health of insect populations and the broader environment.

Safety and Environmental Concerns: As with any chemical compound, the safety and environmental implications of 3-Hydroxy Carbofuran must be rigorously assessed. The modification of carbofuran’s structure might influence its persistence in the environment, its potential to bioaccumulate in organisms, and its overall impact on non-target species. A comprehensive evaluation of these factors is essential before widespread use.