Bromobimane

Improve your advanced biochemical assays and analytical workflows with Bromobimane (CAS No.: 71418-44-5, CAT NO.: SRCB-032), a high-purity monobrominated bimane compound widely used as a reagent for thiol detection and labeling.

Bromobimane is essentially nonfluorescent but selectively reacts with thiol groups, creating highly fluorescent adducts for sensitive quantification and imaging in life science, environmental, and clinical research. With a molecular formula of C₁₀H₁₁BrN₂O₂ and a molecular weight of 271.11 g/mol, it is typically supplied as a light yellow to orange crystalline powder. Offering excellent thiol reactivity, high photostability, and superior purity (≥98%), Bromobimane is ideal for derivatization in HPLC, fluorescence microscopy, and redox biology studies. The compound is hygroscopic, light- and heat-sensitive, and should be stored frozen and protected from light to maintain optimal performance.

Product Highlights

Technical Features & Benefits

• Sensitive Thiol Probe: Selectively detects and labels thiol-containing molecules, producing highly fluorescent derivatives suitable for trace analysis.

• High Purity & Photostability: ≥98% purity and robust fluorescence after derivatization ensure high assay reliability.

• Easy Handling & Versatile Use: Suitable for HPLC, fluorimetry, imaging, and environmental monitoring of reactive sulfur species.

• Nonfluorescent Precursor: Minimal background signal before reaction reduces assay interference and enhances detection limits.

• Light-Sensitive, Stable Storage: Long shelf life if kept frozen and protected from light; handled under subdued light for best results.

Application Areas

• Labeling and quantification of thiols (e.g., glutathione, cysteine) in biological and clinical samples

• Fluorescent detection in HPLC, capillary electrophoresis, and imaging techniques

• Oxidative stress, redox biology, and reactive oxygen/nitrogen species studies

• Environmental monitoring of glutathione and other thiols in water and soil

• Probe development for fluorescence-based sensing and analytical diagnostics

Safety & Handling

• Handling Precautions: Use gloves, eye protection, and lab coat. Avoid inhalation, ingestion, and contact with skin or eyes.

• Storage Recommendations: Store in tightly sealed containers, frozen (<0°C), protected from direct light and moisture. Handle under subdued light to minimize decomposition.

• Disposal: Dispose of waste in accordance with local, regional, and national regulations. Treat as hazardous chemical waste.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Advanced synthesis with thorough quality control ensures high purity and batch-to-batch consistency.
• Custom Synthesis: Flexible solutions for tailored chemical needs, from milligram to kilogram scale, with robust documentation.
• Comprehensive Documentation: Full analytical data (COA, NMR, HPLC) accompanies every order for complete transparency and confidence.
• Responsive Customer Support: Dedicated technical service and collaborative project assistance from inquiry through delivery.

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Empower your fluorescence assays and chemical biology research with SRIRAMCHEM’s premium Bromobimane. Contact us for pricing, samples, or to discuss custom research solutions.