Boc-Tyr(Me)-OH

Enhance your peptide synthesis and biochemical research with Boc-Tyr(Me)-OH (CAS No.: 53267-93-9, CAT No.: SRCB-076), a high-purity N-tert-butoxycarbonyl protected L-tyrosine derivative featuring a methylated phenolic hydroxyl side chain. This modified amino acid provides Boc protection at the amino terminus and methylation on the tyrosine phenol, enabling selective peptide bond formation while modulating side-chain reactivity and hydrophobicity.

Boc-Tyr(Me)-OH is widely used in solid-phase and solution-phase peptide synthesis for incorporating methylated tyrosine residues, aiding the design of peptides with altered biochemical properties and enhanced stability. It has a molecular formula of C₁₃H₁₉NO₄ and a molecular weight of 257.29 g/mol. Typically supplied as a white to off-white crystalline powder, it offers excellent purity (≥98%) and good solubility in common peptide synthesis solvents such as DMF, DCM, and methanol.

Product Highlights

Technical Features & Benefits

• Modified Tyrosine Residue: O-methylation on the phenolic side chain alters hydrophobicity and biochemical properties useful in peptide design.
• Boc Protection: Safeguards the amino terminus for selective peptide coupling with minimal racemization.
• High Purity & Reproducibility: Ensures consistent quality and reliable performance in peptide synthesis and biochemical applications.
• Good Solubility Profile: Compatible with common peptide synthesis solvents facilitating smooth incorporation in various protocols.
• Standard Deprotection: Boc group is removable under mild acidic conditions preserving methylated side-chain integrity.

Application Areas

• Solid-phase and solution-phase peptide synthesis involving O-methyltyrosine residues.
• Production of modified peptides, peptidomimetics, and protein engineering research.
• Studies on peptide hydrophobicity, stability, and functional modifications.
• Biomedical and medicinal chemistry research requiring altered tyrosine functionalities.

Safety & Handling

• Handling Precautions: Use appropriate personal protective equipment including gloves, safety goggles, and lab coat. Avoid inhalation, ingestion, and skin or eye contact.
• Storage Recommendations: Store in a cool, dry, well-ventilated place, protected from light and moisture to maintain stability and purity.
• Disposal: Dispose of chemical waste following local, regional, and national guidelines.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Advanced synthetic control with rigorous quality assurance delivers high purity and batch consistency.
• Custom Synthesis: Flexible production scales and derivative modifications tailored to your research and synthesis needs.
• Comprehensive Documentation: Each batch comes with full COA, NMR, HPLC, and MS for confidence and traceability.
• Responsive Support: Knowledgeable technical and customer service to assist throughout your project lifecycle.

Request a Quote or Sample Today!
Advance your peptide synthesis and biochemical projects with SRIRAMCHEM’s premium Boc-Tyr(Me)-OH. Contact us for pricing, sample availability, or custom synthesis inquiries.