Boc-Tyr(Bzl)-OH

Enhance your peptide synthesis and biochemistry workflows with Boc-Tyr(Bzl)-OH (CAS No.: 2130-96-3, CAT No.: SRCB-074), a high-purity, orthogonally protected L-tyrosine derivative. This compound features a tert-butoxycarbonyl (Boc) group at the α-amino terminus and a benzyl (Bzl) group protecting the phenolic hydroxyl side chain, making it an essential building block in solid-phase and solution-phase assembly of peptides where selective side-chain deprotection is required.
Boc-Tyr(Bzl)-OH is ideal for synthesizing peptides, bioconjugates, and bioactive molecules incorporating tyrosine residues while preventing undesirable side reactions at the phenolic position. With a molecular formula of C₂₀H₂₃NO₄ and a molecular weight of 341.40 g/mol, it is typically supplied as a white to off-white crystalline powder, possessing excellent purity (≥98%) and high stability in standard organic solvents such as DMF, DCM, and methanol.

Product Highlights

Technical Features & Benefits

• Orthogonally Protected Tyrosine: Boc group on the amine ensures stepwise peptide synthesis; benzyl group on the phenolic side chain enables selective deprotection for post-synthetic modifications.
• High Purity & Batch Consistency: Suitable for demanding peptide and medicinal chemistry applications with reproducible performance.
• Excellent Solubility: Readily dissolves in peptide synthesis solvents for convenient handling and synthetic efficiency.
• Mild Deprotection: Boc removable under mild acid; benzyl group removed by catalytic hydrogenation or strong acids.
• Versatile Use: For both solid-phase and solution-phase synthesis of tyrosine-containing peptides and bioconjugates where side-chain integrity is essential.

Application Areas

• Solid-phase and solution-phase peptide synthesis involving tyrosine with protected phenolic group
• Preparation of bioactive peptides, bioconjugates, and enzyme substrates
• Medicinal chemistry projects involving selective post-synthetic modifications
• Development of biochemical probes and research tools incorporating modified tyrosine

Safety & Handling

• Handling Precautions: Wear PPE (gloves, goggles, lab coat); avoid inhalation, ingestion, and direct skin/eye contact.
• Storage: Store tightly sealed in a cool, dry, well-ventilated place away from light and moisture.
• Disposal: Dispose according to local, regional, and national chemical regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Precision-controlled synthesis and rigorous quality control for high batch purity and reproducibility
• Customizable scale and modifications to meet peptide synthesis needs
• Comprehensive analytical documentation, including COA, NMR, HPLC, and MS with every batch
• Responsive customer and technical support

Request a Quote or Sample Today!
Accelerate your peptide synthesis and biochemistry research with SRIRAMCHEM’s Boc-Tyr(Bzl)-OH. For pricing, availability, or custom synthesis, please contact our technical team.