Boc-Thr(Bzl)-OH

Enhance your peptide synthesis and organic chemistry projects with Boc-Thr(Bzl)-OH (CAS No.: 15260-10-3, CAT No.: SRCB-068), a high-purity N-tert-butoxycarbonyl protected L-threonine derivative featuring a benzyl (Bzl) group on the side-chain hydroxyl. This orthogonally protected amino acid enables stepwise incorporation of threonine residues into peptides, facilitating selective coupling and downstream modifications while avoiding side reactions.
The Boc group protects the α-amino terminus, while the benzyl protects the threonine hydroxyl, making it ideal for solid-phase and solution-phase peptide synthesis, natural product synthesis, and complex sequence assembly. The molecular formula is C₁₆H₂₃NO₅ with a molecular weight of 309.36 g/mol. Boc-Thr(Bzl)-OH is typically supplied as a white to off-white crystalline powder, demonstrating high purity (≥98%) and excellent solubility in DMF, DCM, and methanol.

Product Highlights

Technical Features & Benefits

• Orthogonally Protected Threonine: Boc safeguards the amine, benzyl protects the side-chain hydroxyl; ideal for selective, stepwise peptide synthesis.
• High Purity & Reproducibility: Batch-verified purity (≥98%) ensures reliability in solid- and solution-phase sciences.
• Excellent Solubility: Soluble in standard peptide synthesis solvents for ease of use in coupling reactions.
• Mild Deprotection: Boc removable with acid (e.g., TFA); Bzl removable by catalytic hydrogenation or strong acids, compatible with orthogonal synthesis strategies.
• Versatile Building Block: Useful for conventional, cyclic, and modified peptide synthesis, as well as for assembling complex or branched sequences.

Application Areas

• Solid-phase and solution-phase peptide synthesis for targeted and bioactive peptides.
• Construction of peptidomimetics, natural product analogues, and modified proteins.
• Medicinal chemistry and biochemical projects involving hydroxylated peptide modification.
• Development of probes and tools for advanced chemical biology.

Safety & Handling

• Handling Precautions: Use gloves, lab coat, and eye protection; avoid inhalation and direct contact.
• Storage: Store sealed, dry, and protected from light/moisture at room temperature or lower.
• Disposal: Dispose according to institutional and governmental chemical waste regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Precision-controlled synthesis and quality-tested for high purity, supporting batch-to-batch reproducibility.
• Customizable scale and modifications for unique peptide synthesis projects.
• Comprehensive analytical documentation with every lot (COA, NMR, HPLC, MS).
• Responsive technical and commercial support for all stages of your research and development workflow.

Request a Quote or Sample Today!
Accelerate your peptide chemistry and research programs with SRIRAMCHEM’s premium Boc-Thr(Bzl)-OH. Contact us for pricing, technical information, or batch-specific analyses.