Boc-Ser(Bzl)-OH

Advance your peptide synthesis and organic chemistry research with Boc-Ser(Bzl)-OH (CAS No.: 23680-31-1, CAT No.: SRCB-065), a high-purity N-tert-butoxycarbonyl protected L-serine derivative featuring a benzyl (Bzl) protecting group on the hydroxyl side chain. This orthogonally protected amino acid is widely used in solid-phase and solution-phase peptide assembly, enabling selective coupling while preventing side reactions and preserving sensitive functionalities.

Its protected hydroxyl functionality facilitates selective deprotection steps, making it ideal for complex peptide synthesis, post-synthetic modifications, and natural product synthesis. With a molecular formula of C₁₄H₁₉NO₅ and a molecular weight of 273.31 g/mol, Boc-Ser(Bzl)-OH typically appears as a white to off-white crystalline powder. It offers excellent purity (≥98%) and good solubility in common peptide synthesis solvents such as DMF, DCM, and methanol.

Product Highlights

Technical Features & Benefits

• Orthogonally Protected Serine: Boc group protects the amino terminus while benzyl (Bzl) protects the side-chain hydroxyl, allowing selective deprotection steps.
• High Purity & Consistency: Ensures reproducible performance for peptide synthesis and complex molecule assembly.
• Excellent Solubility: Compatible with commonly used organic solvents employed in peptide synthesis workflows.
• Thermal Properties: Suitable melting point with decomposition allows for safe handling and processing.
• Versatility: Ideal for incorporation into peptides requiring selective side-chain modifications, natural product syntheses, and biochemical tool development.

Application Areas

• Solid-phase and solution-phase peptide synthesis involving serine with side-chain protection
• Preparation of peptides, peptidomimetics, and modified biopolymers with controlled hydroxyl functionality
• Medicinal chemistry and natural product synthesis requiring orthogonally protected serine derivatives
• Biochemical probe design and functional group manipulations in complex molecular architectures

Safety & Handling

• Handling Precautions: Use appropriate personal protective equipment (gloves, lab coat, safety goggles). Avoid inhalation, ingestion, and contact with skin or eyes.
• Storage Recommendations: Store tightly sealed in a cool, dry, well-ventilated environment, protected from light and moisture.
• Disposal: Dispose of waste according to local, regional, and national regulations for organic chemical waste.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Advanced synthetic control and stringent quality assurance ensure consistent high purity and batch reproducibility.
• Custom Synthesis: Flexible order quantities and customized protection strategies to meet research and manufacturing needs.
• Complete Documentation: Each lot includes comprehensive Certificate of Analysis (COA), NMR, HPLC, and MS for full traceability and confidence.
• Dedicated Support: Responsive technical and customer service support throughout order placement and project execution.

Request a Quote or Sample Today!
Optimize your peptide synthesis and bioconjugation projects with SRIRAMCHEM’s premium Boc-Ser(Bzl)-OH. Contact our team for pricing, sample availability, or tailored synthesis services.