Boc-Phe-OH

Enable precise peptide synthesis and advanced biochemical research with Boc-Phe-OH (CAS No.: 13734-34-4, CAT No.: SRCB-053), a high-purity N-tert-butoxycarbonyl protected L-phenylalanine derivative. This protected amino acid features a Boc group on the N-terminus, preserving optical purity and facilitating selective peptide bond formation with minimized racemization and side reactions.

Boc-Phe-OH is a critical building block for both solid-phase and solution-phase peptide assembly, and is widely used in the synthesis of phenylalanine-containing peptides, peptidomimetics, and bioactive compounds. Its aromatic side chain provides structural bulk, hydrophobicity, and unique stacking interactions for custom peptide design and medicinal chemistry. The molecular formula is C₁₄H₁₉NO₄ and the molecular weight is 265.31 g/mol. Boc-Phe-OH is typically a white to off-white crystalline powder, offering outstanding purity (≥98%) and excellent solubility in DMF, DCM, and methanol.

Product Highlights

Technical Features & Benefits

• Boc-Protected Phenylalanine: Enables efficient, selective peptide bond formation and reduces the risk of racemization or undesired side reactions.

• Aromatic Side Chain: Provides hydrophobicity and enables pi-stacking, protein folding studies, and incorporation into complex peptide frameworks.

• High Purity & Batch Consistency: Reproducible performance and reliable results in peptide and pharmaceutical R&D.

• Excellent Organic Solubility: Readily dissolves in DMF, DCM, methanol, and ethanol—ideal for modern peptide synthesis protocols.

• Removable Boc Group: Cleaves cleanly under mild acid conditions for seamless peptide elongation or final deprotection.

Application Areas

• Solid-phase and solution-phase peptide synthesis as a protected phenylalanine reagent

• Pharmaceutical development including peptidomimetics and protein engineering

• Preparation of bioactive peptides, enzyme substrates, and reference compounds

• Research in structural biology, molecular interactions, and SAR programs

Safety & Handling

• Handling Precautions: Use lab gloves, goggles, and coat. Avoid inhalation, ingestion, or contact with skin/eyes.

• Storage Recommendations: Store tightly closed in a cool, dry, well-ventilated area away from light and humidity.

• Disposal: Dispose in accordance with institutional or governmental chemical waste regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Batch-controlled production, rigorous QC, and full documentation (COA, NMR, HPLC, MS).
• Custom Synthesis: Flexible scale and derivatives to suit special peptide and pharmaceutical research needs.
• Reliable Quality: Every batch supported by analytical data, ensuring traceability and research confidence.
• Responsive Service: Knowledgeable, prompt assistance from quotation through delivery for seamless project support.

Request a Quote or Sample Today!
Advance your synthetic peptide and pharmaceutical projects with SRIRAMCHEM’s premium Boc-Phe-OH. Contact us for pricing, sample inquiries, or custom synthesis requirements.