Boc-Isonipecotic acid

Advance your peptide synthesis, pharmaceutical, and chemical research with Boc-Isonipecotic acid (CAS No.: 84358-13-4, CAT No.: SRCB-010), a high-purity N-Boc-protected piperidine-4-carboxylic acid (isonipecotic acid). This compound features a piperidine ring substituted at the nitrogen with a tert-butoxycarbonyl (Boc) protecting group and a carboxylic acid at the 4-position, making it a versatile building block for heterocyclic synthesis and functional molecule design.

With molecular formula C₁₁H₁₉NO₄ and molecular weight 229.28 g/mol, Boc-Isonipecotic acid appears as a white to off-white crystalline powder or solid. It is highly stable, with excellent purity (≥98–99%), and is readily soluble in organic solvents such as DMSO and methanol. This derivative is widely used in the preparation of peptide linkers, piperidine-based active pharmaceutical ingredients, and advanced intermediates for drug discovery.

Product Highlights

Technical Features & Benefits

• Boc-Protected Piperidine Acid: Stable tert-butoxycarbonyl (Boc) group enables selective deprotection and functionalization in organic synthesis.

• Versatile Synthetic Intermediate: Widely used in peptide linker synthesis, heterocyclic scaffold designs, and advanced organic molecule construction.

• High Purity & Stability: Provides reliable performance and shelf life under recommended storage; minimal batch-to-batch variation for scientific precision.

• Convenient Handling: Crystalline form is easy to weigh, dissolve, and incorporate into synthetic protocols.

• Good Solvent Compatibility: Compatible with polar organic solvents for flexible use in diverse synthesis and processing workflows.

Application Areas

• Peptide synthesis and linker design for solid-phase and solution-phase protocols

• Medicinal chemistry: precursor for piperidine and pyridine-based bioactive compounds

• Pharmaceutical intermediate for central nervous system (CNS) drug discovery

• Research in heterocyclic compound development and functionalized small molecules

Safety & Handling

• Handling Precautions: Wear protective gloves, safety goggles, and lab coat. Avoid inhalation, ingestion, and skin or eye contact (H315: Causes skin irritation; H319: Causes eye irritation).

• Storage Recommendations: Keep container tightly closed in a cool, dry place, protected from moisture and light.

• Hazard Statements: H315: Causes skin irritation. H319: Causes serious eye irritation.

• Disposal: Dispose according to local, regional, and national regulations for hazardous substances.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Advanced facilities ensure high-purity, reproducible synthesis with comprehensive QA/QC since 2013.
• Custom Synthesis: Scalable solutions for bespoke building blocks and advanced intermediates from milligrams to kilograms.
• Uncompromising Quality: Full Certificate of Analysis (COA) and detailed documentation support every batch.
• Customer-Centric Approach: Responsive service and technical support from inquiry to delivery and beyond.

Request a Quote or Sample Today!
Advance your medicinal chemistry and synthetic workflows with SRIRAMCHEM’s quality-assured Boc-Isonipecotic acid. Contact our expert team for competitive pricing, bulk ordering, samples, or custom synthesis support.