Boc-Glu-OH

Advance your peptide synthesis and biomedical research with Boc-Glu-OH (CAS No.: 2419-94-5, CAT No.: SRCB-061), a high-purity N-tert-butoxycarbonyl protected L-glutamic acid derivative. Featuring a Boc group protecting the α-amino terminus and a free carboxylic acid side chain, this compound is an important building block for stepwise solid-phase and solution-phase peptide synthesis.

Boc-Glu-OH’s protected functionality helps minimize racemization and side reactions during coupling steps, supporting the synthesis of glutamate-containing peptides, peptidomimetics, and biologically active molecules. This derivative has a molecular formula of C₁₀H₁₇NO₆ and a molecular weight of 239.24 g/mol. Typically supplied as a white to off-white crystalline powder, it offers excellent purity (≥98%) and solubility in common peptide synthesis solvents such as DMF, DCM, and methanol. The Boc protecting group is removable under mild acidic conditions, providing synthetic flexibility.

Product Highlights

Technical Features & Benefits

• Boc-Protected Glutamic Acid: Protects the amino terminus facilitating selective peptide bond formation with minimal side reactions or racemization.

• Free Carboxylic Side Chain: Enables further functionalization and contributes to peptide polarity and biological activity.

• High Purity & Reproducibility: Ensures consistent performance in peptide synthesis and biological applications.

• Good Solubility Profile: Compatible with common peptide synthesis solvents, aiding seamless incorporation into synthetic workflows.

• Mild Boc Deprotection: Boc group removable under gentle acidic conditions preserving the free carboxylic acid and stereochemical integrity.

Application Areas

• Solid-phase and solution-phase peptide synthesis involving glutamic acid residues

• Preparation of peptides, peptidomimetics, and biochemical tool compounds

• Structural and functional studies in medicinal chemistry and proteomics

• Intermediate for further chemical derivatization and conjugation

Safety & Handling

• Handling Precautions: Use appropriate PPE such as gloves, safety goggles, and lab coat. Avoid inhalation, ingestion, and skin or eye contact.

• Storage Recommendations: Store tightly sealed in a cool, dry, well-ventilated place protected from light and moisture.

• Disposal: Dispose according to applicable local, regional, and national chemical waste regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Strict quality control and synthesis procedures to ensure high purity and consistent batch quality suitable for peptide chemistry.
• Custom Synthesis: Flexible production scales and modifications tailored to your research and manufacturing needs.
• Comprehensive Documentation: Complete COA, NMR, HPLC, and MS data accompany every batch for traceability and assurance.
• Responsive Customer Support: Dedicated service and technical assistance through all stages of the ordering and research process.

Request a Quote or Sample Today!
Enhance your peptide synthesis and biochemical research projects with SRIRAMCHEM’s premium Boc-Glu-OH. Contact us for pricing, sample availability, or custom synthesis inquiries.