Boc-Asp-OH

Advance your peptide synthesis and biomedical research with Boc-Asp-OH (CAS No.: 13726-67-5, CAT No.: SRCB-052), a high-purity N-tert-butoxycarbonyl protected L-aspartic acid derivative. This crucial amino acid building block features a Boc group on the α-amino terminus and a free carboxylic acid side chain, making it ideal for stepwise solid-phase and solution-phase peptide assembly. Boc-Asp-OH’s protected functionality minimizes racemization and side reactions during peptide coupling, supporting the synthesis of aspartate-containing peptides, bioactive molecules, and structural biopolymers.

With molecular formula C₉H₁₅NO₅ and a molecular weight of 217.22 g/mol, it is typically a white to off-white crystalline powder and boasts high purity (≥98%) plus excellent solubility in DMF, DCM, methanol, and ethanol. The Boc group can be readily removed under mild acidic conditions, affording flexibility in synthetic protocols.

Product Highlights

Technical Features & Benefits

• Boc-Protected Aspartic Acid: Enables robust peptide coupling with minimized racemization and side reactions.

• High Purity & Batch Consistency: ≥98% purity ensures excellent reliability for peptide, pharmaceutical, and biochemical synthesis.

• Excellent Organic Solubility: Compatible with standard peptide synthesis solvents, simplifying workup and scale-up.

• Easy Boc Removal: Boc group can be removed under mild acidic conditions, preserving the functionality of the aspartate residue.

• Versatile Application: Suitable for solid- and solution-phase peptide synthesis, enzyme substrate preparation, and advanced research in protein engineering.

Application Areas

• Protected amino acid building block for solid- and solution-phase peptide synthesis

• Synthesis of aspartic acid-containing peptides and peptidomimetics

• Use in pharmaceutical intermediates, biomaterials, and protein engineering studies

• Research in structure-activity relationships and enzymology

Safety & Handling

• Handling Precautions: Wear suitable lab PPE (gloves, goggles, coat). Avoid inhalation, ingestion, and contact with skin or eyes.

• Storage Recommendations: Keep tightly sealed in a cool, dry, well-ventilated place, protected from light and moisture.

• Disposal: Dispose of waste according to local, regional, and national guidelines for organic chemicals.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: High-purity, batch-controlled synthesis and rigorous QC for reproducible peptide building blocks.
• Custom Synthesis: Flexible support for tailored derivatives, scale-up, and R&D solutions from milligrams to multi-kilogram lots.
• Comprehensive Documentation: COA, NMR, HPLC, and MS data provided for every batch, ensuring traceability and confidence.
• Responsive Service: Timely and knowledgeable expert support for all technical, ordering, and scale-up inquiries.

Request a Quote or Sample Today!
Enhance your peptide chemistry and innovation pipeline with SRIRAMCHEM’s premium Boc-Asp-OH. Contact us for technical support, bulk pricing, or custom synthesis solutions.