Bimane thiocarboxylic acid

Advance your research in bioanalysis, labeling, and material science with Bimane thiocarboxylic acid (CAS No.: 119843-35-5, CAT No.: SRCB-034), a high-purity, thiol-reactive bimane derivative. This compound features a bimane fluorophore core appended with a thiocarboxylic acid functional group, enabling the selective labeling of amine-containing biomolecules, peptides, and proteins by forming stable amide bonds. With a molecular formula of C₁₂H₁₄N₂O₄S and a molecular weight of 282.32 g/mol, it is typically obtained as a light yellow to orange powder, exhibiting high purity (≥95%) and exceptional reactivity for bioconjugation and organic synthesis. Bimane thiocarboxylic acid is favored for its strong fluorescence after derivatization, water and organic solvent compatibility, and its utility in advanced imaging, environmental assays, and custom fluorescent probe design.

Product Highlights

Technical Features & Benefits

• Reactive Carboxylic Acid Function: Enables straightforward amide bond formation with free amines, targeting peptides, proteins, or lysine residues for labeling or cross-linking purposes[4][7].

• Strong Fluorescence Post-Derivatization: Delivers high-contrast signal after reaction, ideal for fluorescence labeling and detection workflows.

• High Purity & Photostability: Batch-verified purity supports reproducibility and stability in advanced chemical and biological applications[5].

• Versatile Compatibility: Soluble in polar organic solvents and useful in both aqueous and non-aqueous systems for bioanalytical and synthetic chemistry.

• Process-Ready: Suitable for custom probe synthesis, analytical reference materials, and protocol standardization in research environments.

Application Areas

• Covalent tagging of peptides, proteins, or small molecule amines for fluorescence-based analysis

• Design and synthesis of advanced fluorescent probes and bioimaging agents

• Labeling in proteomic, metabolomic, and environmental assay workflows

• Research in redox biology, sensor technology, and photochemical studies

• Cross-linking studies for structural and functional investigation of biomolecules

Safety & Handling

• Handling Precautions: Use appropriate PPE: gloves, lab coat, and safety goggles. Avoid inhalation, ingestion, and contact with skin or eyes.

• Storage Recommendations: Store tightly closed at −20°C, protected from light and moisture to prevent degradation.

• Disposal: Dispose according to local, regional, and national regulations as hazardous organic laboratory waste.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Rigorous control and advanced purification deliver products meeting high standards for fluorescence research and custom synthesis.
• Custom Synthesis: Flexible order options: from milligram to commercial scale, with technical support tailored to R&D and analytical projects.
• Comprehensive Quality Assurance: Every batch accompanies COA and thorough analytical documentation (including NMR, HPLC, MS) for full traceability and compliance.
• Dedicated Technical Service: Rapid, solution-oriented customer support for technical queries and project optimization.

Request a Quote or Sample Today!
Strengthen your research programs with SRIRAMCHEM’s high-purity Bimane thiocarboxylic acid. Contact our technical team for pricing, sample availability, or custom synthesis services.