Research ChemicalsBenzyl-2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside
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Name: Benzyl-2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside
CAT No.: SRCB-069
CAS NO : 13343-63-0
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Description
Benzyl-2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside
Elevate your glycoscience, carbohydrate chemistry, and biomedical research with Benzyl-2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside
(CAS No.: 13343-63-0, CAT No.: SRCB-069), a high-purity, orthogonally protected glycoside commonly used as an intermediate in advanced oligosaccharide synthesis. This compound features a benzyl (Bn) glycosidic substitution at the anomeric (C1) position, an acetamido group at the C2-position, and a rigid, acid-labile 4,6-O-benzylidene ring protecting both the C4 and C6 hydroxyls.
The result is a structure designed for regioselective glycosylation, N-acylation, and targeted deprotection—ideal for chemical biology, glycoconjugate synthesis, and ligand development in medicinal chemistry. The molecular formula is C22H25NO6 with a molecular weight of 399.44 g/mol. It typically appears as a white to off-white crystalline powder, possessing excellent purity (≥98%) and stability in standard organic solvents such as dichloromethane (DCM), dimethylformamide (DMF), and methanol.
Product Highlights
| Attribute | Details |
|---|---|
| Chemical Name | Benzyl-2-acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranoside |
| Synonyms | 2-Acetamido-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl benzyl ether; Bn-GlcNAc(4,6-O-benzylidene, 1-O-benzyl) |
| Catalog Number | SRCB-069 |
| CAS Number | 13343-63-0 |
| Molecular Formula | C22H25NO6 |
| Molecular Weight | 399.44 g/mol |
| Appearance | White/off-white crystalline powder |
| Purity | ≥98% |
| Melting Point | Typically 117–121°C (decomp.) |
| Solubility | Soluble in DCM, DMF, methanol, chloroform |
| Storage | Store in a cool, dry, well-ventilated place, protected from light and moisture |
Technical Features & Benefits
- Orthogonal Protection: Benzylidene and benzyl groups enable selective deprotection for stepwise glycan assembly and regioselective modifications.
- N-Acetylglucosamine Core: Mimics biological GlcNAc motifs critical in cell recognition, glycoconjugation, or glycomaterials.
- High Purity & Batch Consistency: Suitable for demanding synthetic, analytical, and medicinal chemistry applications.
- Versatile Synthetic Use: Ideal intermediate for oligosaccharide, glycolipid, glycopeptide, or conjugate vaccine synthesis.
- Stable Storage & Handling: Crystalline solid stable under standard dry, dark storage conditions.
Application Areas
- Intermediate in the synthesis of oligosaccharides, glycopeptides, and glycolipids.
- Building block for chemoenzymatic and chemical glycosylation strategies.
- Development of glycan-based probes, carbohydrate vaccines, and receptor ligands.
- Bioorganic chemistry and drug discovery involving protected amino sugars.
Safety & Handling
- Handling Precautions: Wear laboratory gloves, lab coat, and safety glasses. Avoid inhalation, ingestion, and contact with skin or eyes.
- Storage Recommendations: Store sealed in a cool, dry, well-ventilated area, protected from light, heat, and moisture.
- Disposal: Dispose of waste in accordance with institutional or governmental chemical waste regulations.
Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?
- Advanced chemical synthesis and strict quality control for batch purity and reproducibility.
- Custom synthesis and scalable supply for diverse carbohydrate and glycomaterials research.
- Comprehensive analytical documentation (COA, NMR, HPLC, MS) with every batch.
- Responsive technical and commercial support for efficient project workflow.
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Additional information
| Pack Size | 1gm |
|---|






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