4-(3-Bromopropoxy)-6-fluoro-2H-chromen-2-one

Expand your synthetic and research capabilities with 4-(3-Bromopropoxy)-6-fluoro-2H-chromen-2-one (CAT No.: SRCB-035, CAS No.: NA), a high-purity chromenone (coumarin) derivative functionalized with a bromopropoxy chain at the 4-position and a fluoro substituent at the 6-position.

This compound is designed for use in advanced organic synthesis, fluorescent probe design, and medicinal chemistry as a versatile intermediate. It combines the electron-withdrawing effects of fluorine with the reactivity of the bromoalkoxy group, allowing for further nucleophilic substitutions and cross-coupling transformations. With a predicted molecular formula of C₁₂H₁₀BrFO₃ and an estimated molecular weight of 301.11 g/mol, it is typically a pale yellow solid and offers high purity (≥97%). Its chromenone scaffold and functional handles enable applications in pharmaceutical, analytical, and photophysical research.

Product Highlights

Technical Features & Benefits

• Reactive Bromoalkoxy Handle: Suited for nucleophilic substitution and coupling reactions, enabling derivatization of the chromenone core.

• Fluoro-Substitution: Enhances electron-withdrawing properties for tuning bioactivity and fluorescence in derivatives.

• High Purity & Analytical Grade: Suitable for use in demanding synthetic and screening workflows.

• Aromatic Chromenone Scaffold: Core structure for applications in pharmaceuticals, natural product analogs, and material research.

• Solubility in Organic Solvents: Facilitates solution-phase synthesis, spectroscopy, and analytical applications.

Application Areas

• Intermediate for pharmaceutical and fluorescent probe synthesis

• Precursor for functionalized coumarins and chromones in medicinal chemistry

• Molecular template in organic electronics and material sciences

• Research in nucleophilic aromatic substitution, etherification, and cross-coupling

Safety & Handling

• Handling Precautions: Use personal protective equipment (lab coat, gloves, safety glasses). Avoid inhalation, ingestion, and direct contact.

• Storage Recommendations: Store tightly closed in a cool, dry area; protect from heat, moisture, and direct light.

• Disposal: Dispose of in accordance with local, regional, and national regulations as hazardous chemical waste.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Precision synthesis, quality assurance, and documentation for R&D and bulk applications.
• Custom Synthesis: Flexible order sizes and tailored molecules for advanced research needs.
• Comprehensive Quality: Full analytical documentation (COA, NMR, HPLC, MS) included with every order.
• Responsive Support: Prompt technical assistance and order management tailored to researchers.

Request a Quote or Sample Today!
Advance your synthesis and discovery efforts with SRIRAMCHEM’s specialized 4-(3-bromopropoxy)-6-fluoro-2H-chromen-2-one. Contact us for bulk discounts, sample requests, or custom synthesis inquiries.