Name: 3-Acetyl-11-keto-β-boswellic acid - SRIRAMCHEM
SKU: SHA-03
Price: 10000.00 INR
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Phytochemicals3-Acetyl-11-keto-β-boswellic acid

SKU: SHA-03

Original price was: ₹11,000.00.Current price is: ₹10,000.00.

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Description

3-Acetyl-11-keto-β-boswellic acid

CAS NO: 67416-61-9

CAT NO : SHA-03

Synonym(s): AKBA

Empirical Formula (Hill Notation): C₃₂H₄₈O₅

Molecular Weight:512.72

PROPERTIES

Biological source : Boswellia serrata

Form : powder

storage temp. : −20°C

General description:

Acetyl-11-keto-β-boswellic acid (AKBA) is extracted from the resin of Boswellia serrata.

Application :

3-Acetyl-11-keto-β-boswellic acid (AKBA) has been used:

to test its effects as an anti-proliferating agent on hepatic stellate cells (HSCs) proliferation and synergism in combination with imatinib in in vitro models.
to study its anti-osteoporotic activity on ovariectomy-induced osteoporosis in female Sprague Dawley rats.
in a comparative study with aspirin to test its effects as an anti-inflammatory drug to prevent intestinal adenomatous polyposis in APC^Min/+ mice.

Biochem/physiol Actions

Acetyl-11-keto-β-boswellic acid (AKBA) displays antibacterial and anti-biofilm activities against Staphylococcus epidermidis and S. aureus, respectively. It is an activator of nuclear factor erythroid-2-related factor 2 (Nrf2) and exerts neuroprotective properties against ischemic injury in both in vitro and in vivo studies.

Acetyl-11-keto-beta-boswellic acid is a pentacyclic triterpene that inhibits 5-lipoxygenase in a selective, enzyme-directed, nonredox, and noncompetitive manner. It has also been shown to inhibit topoisomerase I and NF-κB signaling.