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Research Chemicals3-Methoxy-L-Tyrosine Monohydrate

SKU: SRCM-001

28,000.00500,000.00

Name: 3-Methoxy-L- Tyrosine Monohydrate

Cat. No.: SRCM-001

CAS No.: 200630-46-2

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Description

3-Methoxy-L-Tyrosine Monohydrate

Catalogue Number SRCM-001
Chemical Name 3-O-Methyl-L-DOPA Monohydrate
Synonyms 3-Methoxy-4-hydroxyphenylalanine Monohydrate; 3-Methoxy-DOPA Monohydrate; 3-Methoxy-L-tyrosine Monohydrate; 3-O-Methyldopa Monohydrate; L-3-Methoxy-4-hydroxyphenylalanine Monohydrate; L-3-O-Methyl-DOPA Monohydrate; L-4-Hydroxy-3-methoxyphenylalanine Monohydrate;
CAS Number 200630-46-2
Alternate CAS # Free Base: 300-48-1
Molecular Formula C₁₀H₁₅NO₅
Appearance Light Brown to Brown Solid
Melting Point 223-228°C (dec.)
Molecular Weight 229.23
Storage 4°C, Hygroscopic
Solubility Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
Category Standards; Amino Acids; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
Applications 3-O-Methyl-L-DOPA is the major metabolite of L-DOPA via catechol O-methyltransferase (COMT). it is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.
References Soares-da Silva, P., et al.: Brain Res., 863, 293 (2000), Deleu, D., et al.: Clin. Pharmacokinet., 41, 261 (2002)

Biochem/physiol Actions 

it is  is a metabolite of L-Dopa (3-MT), The major metabolite of L-DOPA via catechol O-methyltransferase (COMT).3-MT is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.

3-MT is not a substrate for or an inhibitor of L-amino acid decarboxylase activity. This means that it does not interfere with the production of dopamine from L-dopa. However, 3-MT does have some anti-Parkinsonian effects of its own.

One study found that 3-MT increased the levels of dopamine in the brain of rats with Parkinson’s disease. Another study found that 3-MT improved motor function and reduced symptoms of Parkinson’s disease in humans.

It is, also known as 3-Methylthio-L-Tyrosine or Hordenine, is a naturally occurring compound that has gained attention for its potential health benefits. This unique compound is a derivative of the amino acid tyrosine and holds promise in various areas, including cognitive enhancement, mood support, and physical performance. In this article, we will delve into the properties, mechanisms of action, and potential applications of this product.

Chemical Structure and Properties: It is a derivative of tyrosine, one of the 20 standard amino acids used by cells to synthesize proteins. The chemical structure of it Monohydrate includes an additional methoxy group (-OCH3) and a thioether group (-S-) attached to the tyrosine molecule. This modification imparts unique characteristics to the compound, contributing to its potential physiological effects.

The monohydrate form of it  indicates that it contains one molecule of water. This crystalline form enhances the stability and bioavailability of the compound, making it more suitable for various applications.

Mechanisms of Action: The potential benefits of it are thought to arise from its interactions with neurotransmitter pathways and physiological processes within the body. Some proposed mechanisms of action include:

  1. Dopamine Regulation: Dopamine is a neurotransmitter associated with motivation, mood, and pleasure. 3-Methoxy-L-Tyrosine Monohydrate is believed to support dopamine production and regulation, potentially contributing to improved mood and cognitive function.
  2. Catecholamine Synthesis: Catecholamines, including dopamine, norepinephrine, and epinephrine, play crucial roles in stress response, focus, and alertness. it may influence the synthesis of these neurotransmitters, leading to enhanced cognitive performance and stress resilience.
  3. MAO-B Inhibition: Monoamine oxidase-B (MAO-B) is an enzyme responsible for breaking down neurotransmitters like dopamine. Inhibition of MAO-B activity by it could potentially lead to increased levels of dopamine and other catecholamines.

Potential Applications: The potential applications of 3-DOPA span several areas, including:

  1. Cognitive Enhancement: Due to its effects on dopamine and neurotransmitter regulation, it might contribute to improved cognitive functions such as focus, attention, and memory.
  2. Mood Support: The compound’s influence on dopamine pathways suggests a possible role in mood regulation and emotional well-being.
  3. Physical Performance: Some athletes and fitness enthusiasts explore the use of it, to support energy levels, focus, and endurance during workouts or physical activities.
  4. Stress Resilience: The potential impact on stress-related neurotransmitters could make this compound relevant for managing stress and promoting overall resilience.

 

Additional information

Pack Size

50mg, 100mg, 250mg, 1gm

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