3-Fluoro-4-iodopyridine

Advance your pharmaceutical, agrochemical, and synthetic chemistry research with 3-Fluoro-4-iodopyridine (CAS No.: 22282-75-3, CAT No.: SRCF-003). This compound features a pyridine ring substituted with a fluorine atom at the 3-position and an iodine atom at the 4-position. It is a highly versatile halogenated heterocycle, widely used as a building block for cross-coupling reactions, the synthesis of pharmaceuticals, agrochemicals, and materials science intermediates.

With the molecular formula C₅H₃FIN and a molecular weight of approximately 223.99 g/mol, 3-Fluoro-4-iodopyridine typically appears as a white to pale yellow solid or crystalline powder. The electron-deficient pyridine core and dual halogen substitution facilitate a variety of regioselective functionalizations, making it valuable in modern synthetic protocols, especially for introducing fluorinated and iodinated motifs into advanced molecules.

Product Highlights

Technical Features & Benefits

• Dual Halogen Substitution: Offers notable reactivity in palladium-catalyzed cross-coupling (e.g., Suzuki, Sonogashira) and nucleophilic substitution.
• Pyridine Core: Provides an electron-deficient aromatic system ideal for further functionalization and application in heterocyclic chemistry.
• High Purity: Suitable for research and production of active pharmaceutical ingredients, agrochemicals, and complex molecular scaffolds.
• Solid, Stable Form: Ensures easy handling, precise weighing, and long shelf life with proper storage.
• Versatile Building Block: Used for introducing fluorine and iodine functionalities into advanced molecules, impacting biological activity and physical properties.

Application Areas

• Intermediate in the synthesis of pharmaceuticals and agrochemicals
• Building block for advanced materials and heterocyclic compounds
• Palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig)
• Preparation of radiolabeled tracers, fluorinated analogues, and diagnostics
• Research reagent for exploring halogen effects in medicinal and organic chemistry

Safety & Handling

• Wear appropriate PPE including gloves, goggles, and lab coat
• Avoid inhalation, ingestion, or direct contact with skin/eyes
• Store tightly closed, protected from light, moisture, and high temperatures
• Dispose of chemical waste in accordance with applicable regulations

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Advanced manufacturing and quality control ensure technical grade and high-purity halogenated pyridines
• Capability for custom synthesis and bulk supply for research and commercial needs
• Comprehensive analytical documentation: COA, NMR, HPLC, LC-MS for every product
• Dedicated customer and technical support for smooth order through delivery

Request a Quote or Sample Today!
Accelerate your fluorinated-heterocycle and cross-coupling research with SRIRAMCHEM’s premium 3-Fluoro-4-iodopyridine. Contact our expert team now for pricing, availability, or to discuss custom synthesis projects.