3-Amino-5-methylpyrazole

Advance your heterocyclic pharmaceutical synthesis with 3-amino-5-methylpyrazole (CAS No.: 31230-17-8, CAT No.: SRCP-020). This aminopyrazole serves as a versatile building block for pyrazolo[3,4-b]quinolinones, pyrazolopyridines, and ?-sheet template scaffolds in medicinal chemistry library construction.

[1][2][3][4]

With a molecular formula of C₄H₇N₃ and a molecular weight of 97.12 g/mol, it appears as a white to light yellow crystalline solid with a melting point of 45?47 ?C. Soluble in dichloromethane and methanol, its bifunctional amino-pyrazole system enables diverse cyclocondensation and metal coordination reactions.

[5][6][3][1]?

Product Highlights

?

Technical Features & Benefits

• Bifunctional Heterocycle: Amino group enables acylation/schiff base formation while pyrazole NH supports hydrogen bonding and tautomerism.

[3][1]

• ?-Sheet Template: Forms stable hydrogen-bonded networks with ferrocenoyl-dipeptides for peptide mimicry applications.

[1]

• Cyclocondensation Partner: Reacts with 1,3-dicarbonyls to form pyrazoloquinolinones and fused heterocycles.

[2][4]

• Metal Coordination Ligand: N-donor sites form stable complexes with transition metals for catalysis and bioinorganic studies.

[1]

• Low Melting Solid: 45?47?C melting point facilitates handling and purification in library synthesis.

[6][1]

?

Application Areas

• Synthesis of pyrazolo[3,4-b]quinolin-5-ones and fused heterocyclic pharmaceuticals.

[2][1]

• ?-Sheet mimetic templates for peptide foldamer and protein mimicry research.

[1]

• Ligand for ferrocene-peptide conjugates and bioorganometallic assemblies.

[1]

• Building block for agrochemicals and pharmaceutical intermediates.

[4][7]

• Coordination chemistry reagent for N-heterocyclic metal complexes.

[1]

?

Safety & Handling

• Skin/eye irritant (H315/H319); wear gloves, goggles, lab coat.

[6][1]

• Respiratory irritant (H335); handle in fume hood with good ventilation.

[1]

• Hygroscopic and heat-sensitive; store refrigerated under inert gas.

[6]

• Dispose of as chemical waste per local regulations.

[1]

?

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Specialized expertise in pyrazole building blocks and fused heterocyclic synthesis.

[8][9][10]

• Custom pyrazoloquinolinone and peptide conjugate synthesis from research to scale-up.

[10][11][8]

• Comprehensive analytical support: COA, NMR, HPLC, LC-MS for pharmaceutical development.

[9][12][10]

• Technical collaboration for heterocycle library design and coordination chemistry applications.

Request a Quote or Sample Today! Accelerate your pyrazoloquinolinone, peptide mimicry, and metal complex research with SRIRAMCHEM’s premium 3-amino-5-methylpyrazole. Contact the expert team for pricing, availability, or custom heterocyclic requirements.