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Name: (2S,5S)-2-Carbamoyl-6,6-dimethyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid-tert-butyl ester
CAT No.: SRCC-002
CAS NO : 361440-67-7
- Description
- Datasheet
- Additional information
Description
(2S,5S)-2-Carbamoyl-6,6-dimethyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid-tert-butyl ester
Enhance your advanced organic synthesis and medicinal chemistry workflows with (2S,5S)-2-Carbamoyl-6,6-dimethyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid-tert-butyl ester (CAS No.: 361440-67-7, CAT No.: SRCC-002), a high-purity, sterically and conformationally constrained bicyclic amino acid derivative.
This molecule features a fused cyclopropane-pyrrolidine core, a tert-butyl ester for carboxyl protection, and a carbamoyl functional group, making it an ideal building block in the synthesis of peptidomimetics, enzyme inhibitors, and novel drug scaffolds.
Its molecular formula is C12H20N2O3 with a molecular weight of 240.30 g/mol. Typically supplied as a white to off-white crystalline powder, this compound provides excellent purity (≥98%) and is readily soluble in solids-compatible organic solvents such as DCM, DMF, and methanol, facilitating use in research and process development.
Product Highlights
| Attribute | Details |
|---|---|
| Chemical Name | (2S,5S)-2-Carbamoyl-6,6-dimethyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid-tert-butyl ester |
| Synonyms | t-Butyl (2S,5S)-2-carbamoyl-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-3-carboxylate; Bicyclic β-amino acid tert-butyl ester |
| Catalog Number | SRCC-002 |
| CAS Number | 361440-67-7 |
| Molecular Formula | C12H20N2O3 |
| Molecular Weight | 240.30 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% |
| Melting Point | Approx. 140–145°C (decomposition typical) |
| Solubility | Soluble in DCM, DMF, methanol; sparingly soluble in water |
| Storage | Store tightly sealed in a cool, dry, well-ventilated place, protected from light and moisture |
Technical Features & Benefits
- Bicyclic β-Amino Acid Framework: Provides rigid stereochemistry for peptidomimetic design and enzyme active site mimicry.
- Carbamoyl & tert-Butyl Ester Protection: Enables orthogonal functionalization in stepwise synthesis and prevents premature hydrolysis.
- High Analytical Purity: Guarantees consistent quality and reactivity for demanding synthetic and research uses.
- Solubility & Handling: Easily handled and dissolved in common peptide and small molecule synthesis solvents.
- Application Flexibility: Suitable for use in medicinal chemistry, structure-activity relationship (SAR) studies, and advanced materials research.
Application Areas
- Peptidomimetic synthesis and design of enzyme inhibitors
- Building block in medicinal and supramolecular chemistry
- Advanced materials development involving constrained amino acid units
- Biochemical probe and drug scaffold research
Safety & Handling
- Handling Precautions: Use proper laboratory PPE including gloves, goggles, and lab coat. Avoid inhalation, ingestion, and contact with skin or eyes.
- Storage Recommendations: Keep tightly sealed in a cool, dry, and well-ventilated area, away from light and humidity.
- Disposal: Dispose of waste according to local, regional, and national chemical safety guidelines.
Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?
- Expert Manufacturing: Precision-controlled synthesis and advanced analytical quality control provide exceptional batch-to-batch consistency and purity.
- Custom Synthesis: Scalable and tailored production options available for specialized research and industrial needs.
- Comprehensive Documentation: Every batch accompanied by full Certificate of Analysis (COA), NMR, HPLC, and MS data for scientific confidence and traceability.
- Responsive Customer Support: Knowledgeable technical and sales assistance from inquiry to delivery and beyond.
Request a Quote or Sample Today!
Accelerate your synthesis and pharmaceutical innovation with SRIRAMCHEM’s premium (2S,5S)-2-Carbamoyl-6,6-dimethyl-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid-tert-butyl ester. Contact us for pricing, sample availability, or custom synthesis solutions.
Additional information
| Pack Size | 1gm |
|---|


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