2-Ketoglutaric acid

Advance your biochemical, pharmaceutical, and metabolic research with 2-Ketoglutaric acid (CAS No.: 328-50-7, CAT No.: SRCK-002). Also known as alpha-ketoglutaric acid or 2-oxoglutaric acid, this compound is a key intermediate in the Krebs cycle and amino acid metabolism. It features a dicarboxylic acid with a ketone functional group, playing a vital role in cellular energy transfer, nitrogen metabolism, and biosynthesis of amino acids and nucleotides. Widely used in dietary supplements, biochemical assays, and organic synthesis of fine chemicals, 2-ketoglutaric acid supports physiological and synthetic applications.

Molecular formula: C₅H₆O₅, Molecular weight: 146.1 g/mol. Appears as a white to yellowish crystalline powder with melting point of 113–115 °C and estimated boiling point around 185.7 °C. Soluble in water and alcohols but insoluble in ether, density approximately 1.28 g/cm³. pKa approximately 2.47 at 25°C. It has a logP of –2.08 indicating good aqueous solubility and polarity.

Product Highlights

Technical Features & Benefits

• Central Metabolic Intermediate: Key role in the Krebs cycle and amino acid metabolism.
• Pharmaceutical Importance: Used in synthesis of amino acids, dietary supplements, and fine chemicals.
• Biochemical Research: Serves as substrate and biomarker in metabolic and enzymatic studies.
• Good Solubility & Stability: Easily handled in aqueous and organic media with good shelf-life.
• High Purity: Ideal for analytical, medicinal, and chemical synthesis applications.

Application Areas

• Biochemical and metabolic pathway research
• Production of amino acids and dietary supplements
• Pharmaceutical and fine chemical synthesis
• Enzyme kinetics and substrate development

Safety & Handling

• Precautions: Use recommended PPE including gloves and eyewear. Avoid inhalation, ingestion, and contact with skin and eyes.
• Storage: Keep in sealed containers away from moisture, light, and heat.
• Disposal: Dispose in accordance with local, state, and federal regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Quality Excellence: Manufactured under stringent quality controls with certified purity and batch consistency since 2013.
• Flexible Supply: Scalable volumes and customized packaging tailored to your research or manufacturing needs.
• Comprehensive Documentation: Each batch supplied with Certificate of Analysis (COA) and advanced analytical testing data.
• Dedicated Customer Service: Professional and responsive support helping you optimize your project workflows.

Request a Quote or Sample Today!
Empower your metabolic and pharmaceutical research with SRIRAMCHEM’s 2-Ketoglutaric acid. Contact us for competitive pricing, samples, or custom synthesis options.