2-Chloro-2,4-Difluoroacetophenone

Enhance your pharmaceutical and chemical synthesis projects with 2-Chloro-2,4-Difluoroacetophenone (CAS No.: 51336-94-8, CAT No.: SRCC-009). This high-purity halogenated acetophenone derivative features chlorine and fluorine substitutions on the acetophenone scaffold, making it a valuable intermediate for drug discovery and organic synthesis applications.

With a molecular formula of C₈H₅ClF₂O and a molecular weight of approximately 190.57 g/mol, it is supplied as a white crystalline powder. This compound demonstrates good thermal stability, with a melting point range of 44–51°C, and is commonly used in the synthesis of antifungal agents like fluconazole and other bioactive molecules.

Product Highlights

Technical Features & Benefits

• Halogenated Acetophenone Derivative: Contains chlorine and fluorine atoms which influence reactivity and biological activity.
• Pharmaceutical Intermediate: Key building block in synthesizing antifungal agents like fluconazole and antitrypanosomal compounds.
• Protein Tyrosine Phosphatase Inhibitor: Shows activity in inhibiting SHP-1 and PTP1B enzymes involved in cellular signaling pathways.
• High Purity & Consistency: Manufactured under stringent quality control to ensure reproducibility in research.
• Good Thermal Stability: Melting point supports reliable handling and storage under laboratory conditions.

Application Areas

• Pharmaceutical research focusing on antifungal and antitrypanosomal drug development.
• Synthesis of bioactive halogenated intermediates and heterocyclic compounds.
• Studies on enzyme inhibition, especially targeting protein tyrosine phosphatases SHP-1 and PTP1B.
• Organic synthesis workflows requiring halogenated aromatic ketones.

Safety & Handling

• Precautions: Use appropriate personal protective equipment (PPE) including gloves, lab coat, and safety goggles. Avoid inhalation, ingestion, and contact with skin or eyes.
• Storage: Store in a cool, dry, and well-ventilated area, protected from moisture and light.
• Disposal: Dispose of chemical waste according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Our advanced facilities and experienced team ensure high purity and extreme accuracy production, supporting pharmaceutical innovation and clinical research since 2013.
• Custom Synthesis: Capable of designing and producing unique compounds from milligram to multi-kilogram scales, tailored to your specifications with speed and precision.
• Uncompromising Quality: All products come with comprehensive documentation including COA, NMR, LC-MS, and HPLC data, guaranteeing product identity and purity.
• Customer-Centric Approach: Dedicated support and custom solutions to meet your scientific goals from consultation to delivery.

Request a Quote or Sample Today!
Accelerate your research or product development with SRIRAMCHEM’s quality-assured 2-Chloro-2,4-Difluoroacetophenone. Contact our expert team now for pricing, samples, or custom synthesis inquiries.