Research Chemicals2-bromo-1-(4-nitrophenyl)ethan-1-one
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Name: 2-bromo-1-(4-nitrophenyl)ethan-1-one
CAT No.: SRCB-037
CAS NO : 99-81-0
- Description
- Datasheet
- Additional information
Description
2-Bromo-1-(4-nitrophenyl)ethan-1-one
Advance your chemical synthesis and research projects with 2-Bromo-1-(4-nitrophenyl)ethan-1-one (CAS No.: 99-81-0, CAT No.: SRCB-037), a high-purity aromatic ketone featuring a para-nitro substituted phenyl ring with a bromomethyl ketone functionality.
This compound is widely used as an intermediate in organic synthesis, agrochemicals, and pharmaceutical research due to its reactive bromomethyl ketone group and electron-withdrawing nitro substituent. It has the molecular formula C8H6BrNO3 and a molecular weight of 244.04 g/mol. Typically found as a yellow to orange crystalline powder, it exhibits a melting point of approximately 94–99°C and a predicted boiling point around 325°C. Its high purity (≥97%) and good stability under recommended storage conditions make it ideal for diverse synthetic applications including nucleophilic substitution and coupling reactions.
Product Highlights
| Attribute | Details |
|---|---|
| Chemical Name | 2-Bromo-1-(4-nitrophenyl)ethan-1-one |
| Synonyms | 2-Bromo-4′-nitroacetophenone; 4-Nitrophenacyl bromide; p-Nitrophenacyl bromide |
| Catalog Number | SRCB-037 |
| CAS Number | 99-81-0 |
| Molecular Formula | C8H6BrNO3 |
| Molecular Weight | 244.04 g/mol |
| Appearance | Yellow to orange crystalline powder |
| Purity | ≥97% |
| Melting Point | 94–99°C |
| Boiling Point | Approximately 325°C (predicted) |
| Density | Approx. 1.80 g/cm3 |
| Solubility | Soluble in organic solvents; moderate solubility in water |
| Storage | Store under inert gas (nitrogen or argon) at 2–8°C, protected from moisture and light |
Technical Features & Benefits
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Reactive Bromomethyl Ketone: Offers high reactivity for nucleophilic substitution and cross-coupling reactions in organic synthesis.
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Electron-Withdrawing Nitro Group: Enhances chemical activation of the aromatic ring and improves selectivity in functionalization.
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High Purity & Crystalline Stability: Suitable for precise synthetic applications requiring consistent quality.
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Versatile Intermediate: Widely used in pharmaceutical, agrochemical, and material science research for derivative synthesis.
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Ease of Handling & Storage: Stable under recommended storage conditions with standard safety precautions.
Application Areas
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Intermediate in the synthesis of biologically active molecules, pharmaceuticals, and agrochemicals
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Used in research on electron-deficient aromatic ketones and bromomethyl chemistry
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Precursor for functional fluorescent probes and reactive intermediates
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Applicable in cross-coupling and nucleophilic aromatic substitution reaction development
Safety & Handling
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Handling Precautions: Use appropriate personal protective equipment including gloves, safety goggles, and lab coat. Avoid inhalation, ingestion, and skin or eye contact.
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Storage Recommendations: Store in a cool, dry, well-ventilated place under inert atmosphere, protected from light and moisture.
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Disposal: Dispose of wastes according to local, regional, and national environmental regulations.
Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?
- Expert Manufacturing: Rigorous production and purification standards ensure superior purity and reproducibility for scientific and industrial use.
- Custom Synthesis: Scalable synthetic services tailored to your project needs from mg to kg quantities with analytical documentation.
- Comprehensive Quality Control: Every batch includes detailed Certificate of Analysis (COA) and analytical data supporting identity and purity.
- Customer-Centric Service: Dedicated technical assistance and rapid response to inquiries to support your research goals.
Request a Quote or Sample Today!
Enhance your synthesis and research projects with SRIRAMCHEM’s high-quality 2-Bromo-1-(4-nitrophenyl)ethan-1-one. Contact us for pricing, availability, or custom synthesis inquiries.
Additional information
| Pack Size | 1gm |
|---|






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