2-Benzyloxy-1-methylpyridinium Triflate

Advance your synthetic chemistry and research projects with 2-Benzyloxy-1-methylpyridinium Triflate (CAS No.: 882980-43-0, CAT No.: SRCB-013), a high-purity pyridinium salt bearing a benzyloxy substituent and stabilized with triflate counterion. This reagent, also known as Dudley Reagent or Bn-OPT, is widely applied in organic synthesis, particularly for benzyl protection of alcohols under neutral conditions. It features a molecular formula of C₁₄H₁₄F₃NO₄S and a molecular weight of 349.33 g/mol. Typically supplied as a white to almost white solid powder or crystalline material, 2-Benzyloxy-1-methylpyridinium Triflate is valued for its stability, high purity (≥95–97%), and controlled reactivity. It has a melting point range of approximately 85–91°C and should be stored refrigerated (2–8°C) to maintain its integrity. This reagent is sensitive to heat and widely used in benzylation reactions, enabling selective formation of benzyl esters and ethers in pharmaceutical and materials chemistry.

Product Highlights

Technical Features & Benefits

• Neutral Benzylation Reagent: Promotes selective benzyl protection of alcohols under mild, neutral conditions with high efficiency.

• High Purity & Stability: Ensures reproducible synthetic outcomes and reliable storage stability.

• Solid-State Convenience: Easily handled as a white crystalline or powder solid, avoiding handling issues of liquids.

• Heat Sensitivity: Should be stored cold and protected from heat to maintain quality and prevent decomposition.

• Broad Synthetic Utility: Widely used in pharmaceutical and materials chemistry for constructing benzyl-protected intermediates.

Application Areas

• Selective benzylation of alcohols for intermediate synthesis

• Preparation of benzyl ethers and esters in medicinal and synthetic organic chemistry

• Synthesis of protected intermediates in drug discovery and materials science

• Use as a reagent in lithiation and functional group transformation reactions

Safety & Handling

• Handling Precautions: Use appropriate personal protective equipment including gloves, safety goggles, and lab coat. Avoid inhalation, ingestion, and contact with skin or eyes.

• Storage Recommendations: Store refrigerated at 2–8°C, tightly closed, protected from heat and moisture.

• Disposal: Dispose of waste and residues according to local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Our advanced facilities and expert team provide high-purity batches with consistent quality, trusted worldwide since 2013.
• Custom Synthesis: Tailored synthesis and supply services from milligram to multi-kilogram scales to meet your specific research and production needs.
• Uncompromising Quality: All products are supported by comprehensive Certificate of Analysis (COA) and detailed analytical documentation.
• Customer-Centric Approach: Responsive support and personalized service to help achieve your scientific and product development goals.

Request a Quote or Sample Today!
Accelerate your synthetic and medicinal chemistry projects with SRIRAMCHEM’s quality-assured 2-Benzyloxy-1-methylpyridinium Triflate. Contact our expert team now for pricing, samples, or custom synthesis inquiries.