1,4-Dithioerythritol (DTE)

Enhance your biochemical and synthetic research with 1,4-Dithioerythritol (DTE) (CAS No.: 6892-68-8, CAT No.: SRCD-026). DTE is a highly effective, small-molecule reducing agent frequently used in protein chemistry, enzymology, and molecular biology to maintain proteins in their reduced state by breaking disulfide bonds. DTE is a stereoisomer of the more widely known dithiothreitol (DTT) and is especially valued for its strong reducing power and compatibility with sensitive assay conditions.

With a molecular formula of C₄H₁₀O₂S₂ and a molecular weight of 154.25 g/mol, DTE typically appears as a white crystalline solid with a characteristic odor. It is soluble in water and polar organic solvents, supporting a broad range of biochemical and organic synthesis protocols.

Product Highlights

Technical Features & Benefits

• Potent Reducing Agent: Efficiently reduces disulfide (–S–S–) bonds in proteins and peptides, maintaining cysteine residues in their free thiol form.
• Stable in Solution: Retains reducing power across a range of pH values and in various buffer systems.
• High Chemical Purity: Suitable for sensitive biochemical and analytical assays.
• Water & Solvent Solubility: Compatible with aqueous and polar organic solvents for flexible experimental design.
• Isomer Specificity: Useful as a stereochemical control versus DTT in studies of redox and thiol chemistry.

Application Areas

• Reductive cleavage and prevention of disulfide bridges in protein and enzyme assays
• Preservation of enzyme activity by preventing oxidation of thiol groups
• Sample preparation for SDS-PAGE and other protein analysis methods
• Redox biology studies and chemical synthesis involving free thiol groups
• Comparative studies with dithiothreitol (DTT) for stereospecific reduction

Safety & Handling

• Precautions: Use appropriate personal protective equipment, including gloves, goggles, and a lab coat. Avoid inhalation, ingestion, and direct contact with skin or eyes.
• Storage: Store tightly sealed in a cool, dry, and well-ventilated area, away from strong oxidizers and direct light.
• Disposal: Dispose of in accordance with local, regional, and national regulations for laboratory chemicals.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Our advanced facilities and experienced team ensure every batch is produced with extreme accuracy and high purity. As trusted industry leaders since 2013, our chemical solutions power pharmaceutical innovation, clinical research, and specialized testing worldwide.
• Custom Synthesis: Bring your vision to life! Our accomplished scientists are adept at custom synthesis—designing and producing unique compounds from milligrams to multi-kilogram lots, tailored to your specifications. Whether your needs are for a complex intermediate or novel building block, we deliver uncompromising results with speed and precision.
• Uncompromising Quality: SRIRAMCHEM’s products come with robust documentation, including a full Certificate of Analysis (COA) and advanced analytical data (NMR, LC-MS, HPLC), ensuring you receive molecules with verified identity and exceptional purity for every order.
• Customer-Centric Approach: We value collaborative partnerships. Our responsive support and custom solutions mean your scientific goals are always our top priority—from consultation to delivery and beyond.

Request a Quote or Sample Today!
Accelerate your research or product development with SRIRAMCHEM’s quality-assured 1,4-Dithioerythritol. Contact our expert team now for competitive pricing, samples, or custom synthesis inquiries.