1,3:4,6-Di-O-benzylidene-D-mannitol

Enhance your synthetic carbohydrate and organic chemistry projects with 1,3:4,6-Di-O-benzylidene-D-mannitol (CAS No.: 28224-73-9, CAT No.: SRCD-029). This protected mannitol derivative contains benzylidene groups at the 1,3 and 4,6 positions, making it a versatile intermediate in the synthesis of glycosides, oligosaccharides, and chiral auxiliaries. The compound’s rigid bicyclic acetal structure also enables regioselective transformations key to complex carbohydrate construction.

With a molecular formula of C₂₀H₂₂O₆ and a molecular weight of 358.39 g/mol, it appears as a white to off-white crystalline solid. The compound is sparingly soluble in water but dissolves well in common organic solvents such as dichloromethane, chloroform, and methanol, enabling smooth incorporation into various chemical and pharmaceutical syntheses.

Product Highlights

Technical Features & Benefits

• Double Benzylidene Protection: Renders 1,3 and 4,6 diols inert, facilitating regioselective functionalization at remaining positions in carbohydrate synthesis.
• Stable Bicyclic Acetal Structure: Provides robustness under various organic reaction conditions, supporting downstream deprotection and derivatization.
• Chiral Auxiliary: Widely used as a chiral pool starting material in synthesis of optically active intermediates.
• High Purity: Synthesized and purified for demanding pharmaceutical and chemical research.
• Versatile Solubility: Handles easily in organic solvents, supporting a wide range of synthetic transformations.

Application Areas

• Intermediate in oligosaccharide and glycoside synthesis
• Used for selective chemical modifications in carbohydrate chemistry
• Chiral pool auxiliary in asymmetric synthesis and catalytic processes
• Building block for active pharmaceutical ingredients (APIs) and research chemicals
• Research on protective group strategies for polyhydroxy compounds

Safety & Handling

• Wear appropriate PPE: gloves, goggles, and lab coat
• Store in a cool, dry, well-ventilated environment; avoid moisture and light
• Dispose of chemical waste in accordance with local and national regulations

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert manufacturing with strict quality assurance for high purity and consistency
• Custom synthesis capabilities from milligram to multi-kilogram scale
• Comprehensive analytical documentation: COA, NMR, HPLC, and LC-MS data
• Responsive customer service for technical support and project consultation

Request a Quote or Sample Today!
Accelerate your carbohydrate, asymmetric, and synthetic chemistry programs with SRIRAMCHEM’s premium 1,3:4,6-Di-O-benzylidene-D-mannitol. Contact our expert team for pricing, availability, or to discuss custom synthesis projects.