1,2-O-Isopropylidene-β-D-xylofuranose

Advance your carbohydrate and glycoscience research with 1,2-O-Isopropylidene-β-D-xylofuranose (CAS No.: 20031-21-4, CAT No.: SRCI-015). Also known as 1,2-O-isopropylidene-α-D-xylofuranose, this acetal-protected xylose is a common intermediate in oligosaccharide, nucleoside, and glycoside synthesis.

The isopropylidene group stabilizes the 1,2-hydroxyls of the furanose ring, preventing undesirable reactions and enhancing handling and regioselectivity in stepwise synthetic routes. It features a five-membered sugar ring with preservable chirality, supporting both organic carbohydrate chemistry and biochemistry.

Molecular formula: C₈H₁₄O₅, Molecular weight: 190.19 g/mol. It is a white to almost white crystalline powder or solid, with melting point 68–72 °C, specific rotation [α]₂₀/D −16° to −22° (c=1, H₂O), and density approximately 1.24 g/cm³. Slightly soluble in water and methanol, soluble in DMSO, DMF, and ethanol. Store at room temperature (preferably cool, dark, and dry, <15°C recommended) and protected from moisture—material is moisture sensitive. Purity is typically ≥98% for research use.

Product Highlights

Technical Features & Benefits

• Stable Sugar Acetal Protection: Isopropylidene group blocks 1,2-diol, enabling regioselective reactions for glycoside and oligosaccharide synthesis.
• Useful Glycosylation Intermediate: Allows for controlled, stepwise assembly of carbohydrate chains and for nucleoside analog research.
• Chiral, Crystalline: Supports stereoselective synthesis and pure crystalline isolation.
• Moisture Sensitive: Must be stored tightly sealed and dry to prevent hydrolysis and decomposition.
• High Analytical Purity: Supplied at ≥98% for demanding synthetic and analytical applications.

Application Areas

• Intermediate for the synthesis of oligosaccharides, nucleosides, and specialty glycosides
• Building block for selective glycosylation in carbohydrate chemistry
• Protecting group strategies in organic synthesis
• Research in carbohydrate-based biology, material science, and diagnostics

Safety & Handling

• Precautions: Not hazardous under normal laboratory conditions, but avoid dust and skin/eye contact. Use gloves, safety glasses, and lab coat.
• Storage: Keep tightly sealed, dry, and away from moisture and light; recommended cool, dark storage.
• Disposal: Dispose of in accordance with local, regional, and national regulations for sugar derivatives and research chemicals.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Quality Manufacturing: Expertly produced, high-purity sugar building blocks with batch-to-batch reliability.
• Full Documentation: Supplied with Certificate of Analysis (COA), NMR, and purity data.
• Responsive Service: Technical and logistics teams ready to meet your R&D and production needs.
• Flexible Supply: Available from gram to kilogram scale for both research and scale-up purposes.

Request a Quote or Sample Today!
Support your glycoscience and advanced synthesis with SRIRAMCHEM’s 1,2-O-Isopropylidene-β-D-xylofuranose. Contact us for pricing, samples, or customized documentation to suit your project needs.