1α,25-Dihydroxyvitamin D2

Enhance your biochemical and pharmaceutical research with 1,25-Dihydroxyvitamin D2 (CAS No.: 60133-18-8, CAT No.: SRCD-003). Also known as 1,25-dihydroxyergocalciferol or ercalcitriol, this biologically active form of vitamin D2 plays a crucial role in calcium and phosphate metabolism and supports bone health. It is a steroid-like hormone that functions by binding to the vitamin D receptor (VDR) in target cells, modulating gene expression relevant to calcium absorption and homeostasis.

The compound has a molecular formula of C₂₈H₄₄O₃ and a molecular weight approximately 412.65 g/mol. It typically appears as a white to off-white crystalline solid. Soluble in organic solvents such as DMSO and ethanol, 1,25-Dihydroxyvitamin D2 is widely used in medicinal chemistry, endocrinology research, and as a reference standard for vitamin D metabolism studies.

Product Highlights

Technical Features & Benefits

• Active Hormone Form: The bioactive metabolite of vitamin D2 responsible for calcium and phosphate regulation.
• Vitamin D Receptor Binding: Binds to VDR with steroid-like hormone action regulating gene expression affecting mineral metabolism.
• High Purity & Consistency: Manufactured with stringent quality controls suitable for laboratory and pharmaceutical research.
• Versatile Applications: Supports studies of bone metabolism, endocrine function, and vitamin D-related diseases.
• Pharmaceutical Relevance: Used as a reference standard and in synthesis of analogues for therapeutic development.

Application Areas

• Endocrinology research on calcium and phosphate homeostasis.
• Pharmacological studies focusing on vitamin D receptor activation.
• Development of vitamin D analogues and therapeutic agents.
• Reference standard in metabolism and binding affinity studies.
• Studies on bone health, osteoporosis, and related metabolic disorders.

Safety & Handling

• Precautions: Use appropriate personal protective equipment such as gloves, goggles, and lab coat. Avoid inhalation, ingestion, and contact with skin or eyes.
• Storage: Keep tightly sealed, stored in a cool, dry, and dark place to maintain stability and prevent degradation.
• Disposal: Dispose of chemical waste in accordance with local, national, and international regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Our state-of-the-art facilities and experienced team ensure every batch meets high purity and accuracy standards. Trusted globally since 2013 to support pharmaceutical innovation and life science research.
• Custom Synthesis: Capable of delivering tailored synthesis projects, from milligram to multi-kilogram scales, to meet your specialized research needs swiftly and precisely.
• Comprehensive Documentation: Each product includes a full Certificate of Analysis (COA), NMR, HPLC, and MS data to confirm identity, purity, and consistent quality.
• Customer-Centric Support: Dedicated scientific and technical assistance from inquiry through delivery, ensuring your project’s success.

Request a Quote or Sample Today!
Advance your vitamin D metabolism and pharmaceutical research with SRIRAMCHEM’s premium 1,25-Dihydroxyvitamin D2. Contact our expert team now for pricing, samples, or custom synthesis inquiries.