Methyl N-(tert-butoxycarbonyl)-O-methyl-L-serinate

Advance your peptide synthesis, protecting group chemistry, and organic synthesis research with Methyl N-(tert-butoxycarbonyl)-O-methyl-L-serinate (CAS No.: 134167-07-0, CAT No.: SRCM-020). This compound is a doubly protected serine derivative—bearing a tert-butoxycarbonyl (Boc) protecting group on the amino terminus and a methyl ether on the hydroxyl—making it a versatile building block for solid-phase peptide synthesis (SPPS), combinatorial chemistry, and the preparation of modified amino acids.

The compound has a molecular formula of C₁₀H₁₉NO₅ and a molecular weight of approximately 233.26 g/mol. It appears as a white to off-white solid or crystalline powder. It is soluble in organic solvents such as dichloromethane, methanol, and ethyl acetate. For optimal stability and purity, store tightly sealed in a cool, dry place protected from moisture and light.

Product Highlights

Technical Features & Benefits

• Doubly Protected Serine: Both the amino and hydroxyl groups are protected for controlled, selective deprotection and activation in peptide synthesis.
• High Purity and Storage Stability: Produced to research-grade specifications, providing reproducibility and long shelf life.
• Synthetic Versatility: Suitable for use in SPPS, Fmoc/t-Boc strategies, and medicinal chemistry projects.
• Process Compatibility: Good solubility in common peptide synthesis solvents allows efficient coupling and compatibility with automated platforms.
• Comprehensive Documentation: Supplied with Certificate of Analysis (COA) and analytical data such as NMR and HPLC on request.

Application Areas

• Peptide and peptidomimetic synthesis (SPPS and solution-phase)
• Synthesis of modified or protected amino acids
• Pharmaceutical intermediate for combinatorial libraries
• Preparation of protected serine segments in peptide drugs
• Research on controlled deprotection strategies

Safety & Handling

• Use appropriate personal protective equipment (gloves, safety glasses, lab coat)
• Avoid inhalation, ingestion, and skin or eye contact
• Store in original container, sealed, away from moisture and direct sunlight
• Dispose of chemical waste according to local, regional, and national regulations

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• High quality and batch-to-batch reproducibility
• Full analytical support and technical assistance for custom projects
• Research and industrial scale availability
• Responsive customer support

Request a Quote or Sample Today!
Advance your synthetic and peptide chemistry research with SRIRAMCHEM’s premium methyl N-(tert-butoxycarbonyl)-O-methyl-L-serinate. Contact our specialist team today for pricing, technical documentation, or custom synthesis.