H-Gly-OtBu·HCl

Advance your peptide synthesis and medicinal chemistry research with H-Gly-OtBu·HCl (CAS No.: 27532-96-3, CAT No.: SRCG-006). This compound is the hydrochloride salt of glycine with the carboxyl group protected as a tert-butyl (OtBu) ester, providing a stable intermediate suitable for solid-phase and solution-phase peptide synthesis. The hydrochloride stabilizes the free amino group, improving handling and shelf life.

The molecular formula is C₇H₁₅NO₂·HCl and the molecular weight is approximately 171.66 g/mol. Typically supplied as a white to off-white crystalline solid, H-Gly-OtBu·HCl is soluble in common organic solvents such as methanol, ethanol, dichloromethane, and dimethylformamide, facilitating its use in diverse synthetic and peptide assembly protocols.

Product Highlights

Technical Features & Benefits

• Tert-Butyl Ester Protection: Protects the carboxyl group of glycine, allowing selective peptide bond formation while preventing side reactions during synthesis.
• Hydrochloride Salt: Stabilizes the amino group improving compound stability and ease of handling.
• High Purity & Consistency: Produced under stringent quality control to ensure reproducible results and efficient coupling in peptide synthesis.
• Wide Solvent Compatibility: Soluble in multiple organic solvents commonly used in peptide synthesis, enabling versatile synthetic applications.
• Versatile Intermediate: Suitable for use in solid-phase and solution-phase peptide synthesis, organic transformations, and medicinal chemistry research.

Application Areas

• Intermediate and building block for solid-phase and solution-phase peptide synthesis (SPPS and LPPS).
• Used in synthesis of peptides, peptidomimetics, and derivatives involving glycine residues.
• Applicable in medicinal chemistry, biochemical studies, and protein engineering.
• Suitable for organic synthetic routes requiring protected amino acid esters.
• Precursor for the preparation of modified peptides and bioactive compounds.

Safety & Handling

• Wear appropriate personal protective equipment including gloves, lab coat, and eye protection.
• Avoid inhalation, ingestion, and contact with skin or eyes.
• Store in a tightly sealed container in a cool, dry, well-ventilated area protected from moisture and light.
• Dispose of chemical waste in accordance with local, regional, and national regulations.

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert manufacturing with stringent quality assurance guaranteeing high purity and batch-to-batch consistency since 2013.
• Reliable supply of research-grade glycine tert-butyl ester hydrochloride with comprehensive analytical documentation including COA, NMR, HPLC, and LC-MS.
• Custom synthesis and scalable production services adapted to your peptide synthesis and pharmaceutical development needs.
• Responsive technical support and dedicated customer service to assist throughout your research and development projects.

Request a Quote or Sample Today!
Enhance your peptide synthesis and medicinal chemistry research with SRIRAMCHEM’s premium H-Gly-OtBu·HCl. Contact our expert team now for pricing, sample availability, or custom synthesis inquiries.