Ethyl Isonipecotate (CAT No.: SRCE-010, CAS No.: 1126-09-6) is a versatile pharmaceutical intermediate and research chemical widely used in organic synthesis and medicinal chemistry.

Product Overview

Chemical Name: Ethyl Isonipecotate
Synonyms: 4-Piperidinecarboxylic Acid Ethyl Ester, Isonipecotic Acid Ethyl Ester, Ethyl 4-piperidinecarboxylate, Piperidin-4-carboxylic Acid Ethyl Ester
Molecular Formula: C₈H₁₅NO₂
Molecular Weight: 157.21 g/mol
Assay: 98% purity
Appearance: Clear, colorless to slightly brown liquid
Boiling Point: 203–205°C
Density: 1.02 g/mL at 25°C
Solubility: Miscible with ethanol, acetone, and fully miscible with water.

Key Features & Benefits

• High Purity (98% or higher): Ensures reliability in research and synthesis.

• Versatile Building Block: Favored for the synthesis of:

  • Antipsychotic and analgesic pharmaceuticals

  • Inhibitors, antagonists, and fused-pyrimidine derivatives

  • GPR119 agonists and specialty fine chemicals.

• Excellent Solubility: Suitable for a wide variety of organic reactions due to full miscibility with water and organic solvents.

• Industry Standard Quality: Conforms to strict quality standards, often supplied at high purity with low residual solvents, ISO certification where applicable.

Applications

• Pharmaceutical Synthesis:

  • Used as a key intermediate in the preparation of antipsychotic drugs, analgesics, and cardiovascular therapy candidates.

  • Employed in the synthesis of SMN (Survival Motor Neuron) protein modulators, β-aryl and β-amino-substituted esters, and as a precursor for RhoA inhibitors.

• Fine & Specialty Chemicals:

  • Integral for chiral catalysts, specialty polymers, and custom synthesis requiring high chemical integrity.

• Research and Development:

  • Valuable for medicinal chemistry projects and preparation of novel heterocyclic scaffolds.

Technical Specifications

Frequently Asked Questions

Q: What are the primary uses of Ethyl Isonipecotate?
A: It is a pharmaceutical building block, mainly for synthesis of active pharmaceutical ingredients and advanced intermediates, including inhibitors, antagonists, and specialized medicinal compounds.

Q: Is Ethyl Isonipecotate hazardous?
A: It is generally not classified as hazardous for transport, but should be handled following good laboratory practices; consult the SDS for detailed safety measures.

Q: How should Ethyl Isonipecotate be stored?
A: Store in a tightly closed container, in a cool, dry, and well-ventilated place, away from strong oxidizing agents.

Order Ethyl Isonipecotate Today

• Available pack sizes: Custom for research and industrial scale

• Global shipping and technical support available

• Bulk discounts and custom synthesis on request

Advance your pharmaceutical research and synthesis with premium-grade Ethyl Isonipecotate—your trusted building block for innovative chemistry.