H-Asp(OtBu)-OtBu.HCl

Unlock superior peptide synthesis and organic chemistry applications with H-Asp(OtBu)-OtBu.HCl (L-Aspartic acid di-tert-butyl ester hydrochloride, CAS No.: 1791-13-5, CAT No.: SRCA-015). This high-purity, white to almost white crystalline solid features an aspartic acid backbone doubly protected with tert-butyl ester groups at both the α- and β-carboxyl positions and presented as the stable hydrochloride salt.

With a molecular formula C₁₂H₂₄ClNO₄ and a molecular weight of 281.78 g/mol, H-Asp(OtBu)-OtBu.HCl is engineered for precision and consistency in solid-phase peptide synthesis (SPPS), Fmoc/tBu-based protocols, and advanced custom peptide assembly. Its exceptional purity (≥98%) and well-characterized solubility in methanol and organic solvents make it ideal for incorporation into multi-step synthetic workflows, ensuring minimal racemization and selective deprotection during demanding chemical processes. This reagent is routinely employed in pharmaceutical research, peptide sequence elongation, and the creation of protected amino acid building blocks for complex organic transformations.

Product Highlights

Technical Features & Benefits
Protected Aspartic Acid Building Block: Features two tert-butyl (OtBu) blocking groups, enabling selective deprotection in advanced peptide syntheses and minimizing racemization.

High Purity: Ideal for solid-phase peptide synthesis (SPPS), Fmoc/tBu strategies, and pharmaceutical or biochemical research.

Superior Stability: Handles well under recommended refrigerated storage, maintaining reactivity and minimizing degradation.

Versatile Compatibility: Soluble in common organic solvents; integrates easily into multi-step synthetic protocols.

Application Areas
Solid-phase and solution-phase peptide synthesis (SPPS)

Research in biochemistry, molecular biology, and medicinal chemistry

Synthesis of protected amino acid derivatives for pharmaceutical intermediates

Safety & Handling
Hazard Statements: Harmful if swallowed (H302), causes skin and eye irritation (H315, H319), may cause respiratory irritation (H335).

Precautions: Use gloves, protective eyewear, and lab coat. In case of contact, flush with water and seek medical attention if necessary.

Disposal: Dispose of in accordance with local regulations; avoid release to the environment

Why Choose SRIRAMCHEM Laboratories Pvt. Ltd.?

• Expert Manufacturing: Our advanced facilities and experienced team ensure that every batch of products are produced with extreme accuracy and high purity. As trusted industry leaders since 2013, our chemical solutions power pharmaceutical innovation, clinical research, and specialized testing worldwide.
• Custom Synthesis: Bring your vision to life! Our accomplished scientists are adept at custom synthesis—designing and producing unique compounds from milligrams to multi-kilogram lots, tailored to your specifications. Whether your needs are for a complex intermediate or novel building block, we deliver uncompromising results with speed and precision.
• Uncompromising Quality: SRIRAMCHEM’s products come with robust documentation, including a full Certificate of Analysis (COA) and advanced analytical data (NMR, LC-MS, HPLC), ensuring you receive molecules with verified identity and exceptional purity for every order.
• Customer-Centric Approach: We value collaborative partnerships. Our responsive support and custom solutions mean your scientific goals are always our top priority—from consultation to delivery and beyond.

Request a Quote or Sample Today!

Accelerate your research or product development with SRIRAMCHEM’s quality-assured products.Contact our expert team now for competitive pricing, samples, or customs synthesis inquiries.